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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG
2 m. ~! Y% S# @6 f; ?5 G, ^. T9 q1 N如果是中国长大的,英语能到这种程度真是很不简单。5 x$ i+ V7 T* D" {' O9 O& D. o: L
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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It is a shame to see Nature — which nearly all scientists, including myself3 n S8 ?! S' O8 N# ~; [
, regard as one of the most prestigious and influential physical-science
, d, F2 t6 P# ?# nmagazines — publish a thinly veiled biased article like this. Granted, this3 f- Y, p- ~6 v f U3 P }& Z
is not a peer-reviewed scientific article and did not go through the, V6 S! {2 p+ R: l7 T8 F7 j. p
scrutiny of picking referees. But to serve as a channel for the general) u% y+ d2 o- }
populace to be in touch with and appreciate science, the authors and editors
; ^) p% n" v$ G3 o- p! |5 lshould at least present the readers with facts within the proper context,
# o0 Z0 a; o0 |" @8 D! ^* Owhich they blatantly failed to do.
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7 ~! y$ U1 T9 ~8 d# _7 AFirst, to identify Ye’s performance increase, Ewen Callaway compared her7 a, l; d, R$ V5 a5 _+ `
Olympic 400-metre IM time with her performance at the World Championships in) n( q# t. x4 b: G7 b
2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “( P+ w! u: B- H% I% ?8 A
anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
! e; U5 w3 O1 {) f, f4 j' z% ?personal best was 4:33.79 at the Asian Games in 2010. This leads to an
& O6 w. o" n% h: W5 ^) p9 q! D" ]4 uimprovement of 5.38 seconds. In a sporting event in which 0.1 s can be the( W. S* ~9 O( E; y( F( n
difference between the gold and silver medal, I see no reason for 5.38 s to
4 k+ R5 _! z5 t, `, g! f J7 r# P/ Gbe treated as 7 s.
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Second, as previously pointed out, Ye is only 16 years old and her body is
' F6 v! m1 F5 n8 X) v& tstill developing. Bettering oneself by 5 seconds over two years may seem
* O2 j2 h: [) Y) Y; Q8 ?: [+ `: {impossible for an adult swimmer, but it certainly happens among youngsters.
$ d/ ?! B2 o' T7 AAn interview with Australian gold medallist Ian Thorpe revealed that his 400. U" ~ K1 ^3 v* p0 m
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.
/ y2 l" W- [* R9 D& SFor regular people, including Callaway, it may be hard to imagine what an+ w2 B7 P$ z2 [6 A9 Q
elite swimmer can achieve as he or she matures and undergoes scientific and
7 V* f4 y9 ?8 R, X" M5 R; h* ipersistent training. But jumping to the conclusion that it is “anomalous”
# b5 [, p+ b/ G, R7 Z# f, o Ebased on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.4 E5 ^ }5 B3 |$ p& X
; E. J$ s$ h! t3 FThird, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook
" A# u' }' h0 dexample of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in
; \* c) H3 T' P7 L W$ H9 K5 i% u0 l( jthe last 50 metres, but Lochte had a huge lead in the first 300 metres, so
* J& A+ r7 c# x! w' X7 z0 F/ |he chose not to push himself too hard and to conserve his energy for later
7 b1 A6 w, i0 k ^events (whether this conforms to the Olympic spirit and the ‘use one’s
3 g( x+ ^7 e) R: K5 x' mbest efforts to win a match’ requirement that the Badminton World* T) N/ H, D8 e# S8 `" V0 H
Federation recently invoked to disqualify four badminton pairs is another2 r) x9 z' h2 ^' r
topic worth discussing, though probably not in Nature). Ye, on the other$ j! k: N( x& x* t( ?
hand, was trailing behind after the first 300 metres and relied on freestyle
% J7 V, \( A& I& _3 ^, in which she has an edge, to win the race. Failing to mention this; a0 w8 N3 m3 \7 x6 a' j8 X2 H
strategic difference, as well as the fact that Lochte is 23.25 seconds e6 A4 ]! B) K% p! ~0 v
faster (4:05.18) than Ye overall, creates the illusion that a woman swam
$ g, ~/ P; k; c2 Bfaster than the best man in the same sport, which sounds impossible. Putting
. U" g" D9 p% [" \* n; j! \' Kaside the gender argument, I believe this is still a leading question that
9 s/ x' m! x# \: |8 _2 zimplies to the reader that there is something fishy going on.
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Fourth is another example of cherry-picking. In the same event, there are8 {( ^7 W8 Y. S# n0 `9 N: E% M) q2 N
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
# S# ~1 w b* x! \4 `9 d; a& Qs) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s0 D+ v1 h! _& n: j3 H% ?/ B; `
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns
' V, t" V+ D" j* `out, if we are just talking about the last 50 metres in a 400-metre IM,( z, q# l( }9 M$ L" a% \) b2 ?
Lochter is not the example I would have used if I were the author. What kind) \' x/ Z6 y" Q2 Z: z* d$ W6 H+ @1 M
of scientific rigorousness is Callaway trying to demonstrate here? Is it
+ I6 S: h( _+ D1 clogical that if Lochter is the champion, we should assume that he leads in
8 M9 e( `6 o+ y) ?- D$ \$ Xevery split? That would be a terrible way to teach the public how science* w7 Y! z4 u) b( i9 L$ K: P3 v: n
works.
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and/ _! R: B7 M* O* n6 {
implies that a drug test cannot rule out the possibility of doping. Is this
3 ^1 b4 i a# s; Skind of agnosticism what Nature really wants to teach its readers? By that& Q* C) n4 J! ^2 [. d/ N6 N# @
standard, I estimate that at least half of the peer-reviewed scientific1 N& f- A y; K. }, D% a3 r
papers in Nature should be retracted. How can one convince the editors and
* J! G C$ a- h ^$ yreviewers that their proposed theory works for every possible case? One
$ E3 {) A! s" K: Y! _cannot. One chooses to apply the theory to typical examples and to- {/ [. z w' Q+ S0 c [! m
demonstrate that in (hopefully) all scenarios considered, the theory works- { g/ C7 H ]3 F9 j: F( n
to a degree, and that that should warrant publication until a counterexample4 n3 B( b8 E' T2 h7 R
is found. I could imagine that Callaway has a sceptical mind, which is
- J" ~+ v [! L) b8 q# Z+ e2 S/ Pcrucial to scientific thinking, but that would be put to better use if he
* i5 ?8 p- l" `% G; wwrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
- q6 [* @/ ?* \. Nadvanced, non-detectable drug that the Chinese have come up with in the
3 L* L+ `+ I9 ^2 u/ Kpast 4 years (they obviously did not have it in Beijing, otherwise why not" y- i; ~' @9 s
use it and woo the audience at home?), based on data and rational derivation
- `* l, y4 W1 y t+ d% T3 C. This article, however, can be interpreted as saying that all athletes are
% [7 k3 K; t9 b+ J# l: m+ s9 l2 i) Qdoping and the authorities are just not good enough to catch them. That may
/ V* A6 x2 j Z* U: V0 b, Ebe true, logically, but definitely will not make the case if there is ever a
( m6 M& W. j, z8 M# c, p: t1 M8 {( Y* ehearing by the governing body for water sports, FINA, to determine if Ye
5 _2 t% H( v+ R* G! V) Shas doped. To ask whether it is possible to obtain a false negative in a: l, [2 M6 E9 W- R1 t4 J
drug test looks like a rigged question to me. Of course it is possible:9 Q+ A$ n: o* @2 u1 \" Q3 [
other than the athlete taking a drug that the test is not designed to detect" B# T5 N: z" i& [
, anyone who has taken quantum 101 will tell you that everything is
- ~% z8 F' V6 Tprobabilistic in nature, and so there is a probability that the drug in an* J: p8 @2 u0 [5 f
athlete’s system could tunnel out right at the moment of the test. A slight
& [! C' k1 k3 _* O# d0 [chance it may be, but should we disregard all test results because of it?
* @2 ~) [1 a. L0 W7 p: e/ tLet’s be practical and reasonable, and accept that the World Anti-Doping( W [* s2 }! @
agency (WADA) is competent at its job. Ye’s urine sample will be stored for5 L3 ^* \; g& h( K, Y
eight years after the contest for future testing as technology advances.% V0 V5 ?+ H7 ]8 N% q
Innocent until proven guilty, shouldn’t it be?
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* }' e5 K9 o2 d9 }, _& xSixth, and the last point I would like to make, is that the out-of-9 t) V+ P4 s# ]) B, X% @
competition drug test is already in effect, which Callaway failed to mention
2 `7 P' V5 q3 W) ] L1 r. As noted in the president of WADA’s press release, drug testing for
9 ?, Q7 S/ r. c VOlympians began at least six months before the opening of the London
( z! T# X4 `) p6 EOlympics. Furthermore, 107 athletes have been banned from this Olympics for2 u+ m# K! {3 M5 R" ~1 y6 D5 ~
doping. That may be the reason that “everyone will pass at the Olympic6 W- k3 b: c$ W1 z* M9 u
games. Hardly anyone fails in competition testing” — those who did dope
8 p9 n' G1 R- |9 f' w) p) phave already been caught and sanctioned. Callaway is free to suggest that a( E9 g( r$ U5 m4 q
player could have doped beforehand and fooled the test at the game, but this% @- \' r, Y0 y3 X3 o4 J6 H$ `
possibility is certainly ruled out for Ye.) ?3 B) \% J2 }6 |- _2 {/ X
" m8 i C" o- `/ M ]1 VOver all, even though Callaway did not falsify any data, he did (+ q- ^! `7 W" Q1 I1 T) A
intentionally or not) cherry-pick data that, in my view, are far too
1 L9 ^4 F; P8 ?- t {: m4 u' Csuggestive to be fair and unbiased. If you want to cover a story of a V9 ^* f7 d2 i! e3 s+ ^
suspected doping from a scientific point of view, be impartial and provide
" V: M- \2 N" ? [% `, \" Q2 pall the facts for the reader to judge. You are entitled to your
1 j, u# S. _( v& x* n- D: }- |interpretation of the facts, and the expression thereof in your piece,
+ c" {! y6 M9 n ?/ w/ A9 p. Texplicitly or otherwise, but showing only evidence that favours your3 v; D7 `2 v% y' T/ B0 W9 ?# E# A
argument is hardly good science or journalism. Such an article in a journal
6 Z9 x2 ]; c/ o$ w5 Z- s0 m# qsuch as Nature is not an appropriate example of how scientific research or
2 z3 b& J- p2 p1 U3 Greporting should be done. |
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